8/28/2023 0 Comments Normal peak flowHowever, the research studies on the reference value of PEF are rarely reported. There are nearly 1.4 billion Chinese in the world, indicating a huge medical need. PEF is recommended by the WHO, especially for low-resource settings in low- and middle-income countries ( 11). Meanwhile, peak expiratory flow (PEF) was an essential index used to assess response to asthma treatment, short- or long-term monitoring of asthma ( 4, 9), or to evaluate triggers for worsening symptoms and screening of COPD ( 10). The peak flow meter is a handy, easy-to-use tool, which is convenient and cost-effective for investigation and personal care ( 9). Thus, it is important to seek a convenient, fast, and feasible method for early screening and disease surveillance. In 2015, disability-adjusted life years caused by COPD were 15,389,017 and 1,797,438 by asthma in China ( 3). From 1990 to 2015, the prevalence of asthma and COPD globally increased by 44.2 and 12.6%, respectively ( 3). Interventions to improve lung functions or to prevent respiratory disease should be paid more attention to factors associated with PEF.Īsthma and chronic obstructive pulmonary disease (COPD), as two of the most common obstructive airway diseases ( 1), are serious public health problems worldwide ( 2– 4), especially in China ( 5– 8). The reference values for low PEF could provide reference standards for epidemiological studies and clinical practices in the future. Meanwhile, the prevalence of low PEF was 3.94 and 3.32% for men and women, respectively.Ĭonclusions: Age- and sex-specific centiles of standardized PEF for the middle-aged and elderly Chinese population were estimated. The mean PEF values were 367.10 and 253.00 L/min for men and women, respectively. Age and smoking status were negatively associated with PEF significantly in both men and women ( P < 0.05). Height, weight, handgrip strength, and residence in rural were positively associated with PEF. The value of PEF decreased with age in both men and women. Results: The PEF was higher in men than women across all age subgroups. Multiple linear regression analysis was used to determine the associations between risk factors and PEF. The distributions of standardized PEF terciles stratified by sex and age were reported. The PEF was measured using a peak flow meter in liters per minute. Methods: There were 8,914 participants who were included for risk factor analysis and 5,498 participants included for reference value analysis. Thus, this study aimed to determine age- and sex-specific reference values of PEF in the middle-aged and elderly Chinese population. However, few studies have focused on the reference of PEF in China, especially in middle-aged and elderly people. 4Disease Prevention and Control Center of Shahekou District of Dalian City, Dalian, Chinaīackground: Peak expiratory flow (PEF), as an essential index used for screening and monitoring asthma, chronic obstructive pulmonary disease, and respiratory mortality especially in the elderly, is recommended for low-resource settings in low- and middle-income countries. 3Safety and Environment Protection Technology Supervision Center, Liaohe Oilfield Company, Panjin, China. 2Department of Otorhinolaryngology-Head and Neck Surgery, Shengjing Hospital, China Medical University, Shenyang, China.1Department of Clinical Epidemiology, Shengjing Hospital of China Medical University, Shenyang, China.Chao Ji 1, Yang Xia 1, Huixu Dai 1, Zhiying Zhao 1, Tiancong Liu 2, Shuhui Tong 3, Xiaohang Zhang 4 and Yuhong Zhao 1 *
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